Chen Ling Lab

Synthetic Microbiology & Biomanufacturing

We decode the "how" and "why" of bacterial adaptation. By understanding non-model microbes, we engineer sustainable chemicals and discover novel genetic tools.

Research Focus

🧬 Metabolic Engineering

Enhancing efficiency of bulk chemical synthesis in non-model microorganisms through metabolic engineering and laboratory adaptive evolution using DBTL cycle.

🔬 Multi-omics Analysis

Deciphering metabolic mechanisms of non-model microorganisms using multi-omics approaches to achieve optimal synthetic pathways.

✂️ Genome Editing

Investigating transposase-mediated genome rearrangement during adaptive evolution and developing novel genome editing tools.

Principal Investigator

Chen Ling

Chen Ling (凌晨), PhD

Associate Professor

School of Life Sciences, Xiamen University

Dr. Chen Ling completed postdoctoral research at the National Renewable Energy Laboratory (NREL) from 2019 to 2023 and obtained his PhD from Tsinghua University in 2019. Before that, he graduated from China Agricultural University in 2014, with a BS degree. The lab focuses on understanding "how" and "why" in microbial metabolism and adaptation through synthetic biology approaches.

Latest News

May 2026

🎉 Paper accepted in Metabolic Engineering! Our paper "Engineering Complex Phenotypes in Halomonas bluephagenesis TD01 via Large-Fragment Manipulation and Multiplex Base Editing" led by Yu-Hang Zhang, Yuan Yuan, and Bai-Tao Chen has been accepted by Metabolic Engineering. Congratulations to the team!

May 27

🎓 Master's Thesis Defense — Yuan Yuan will present her master's thesis defense on Wednesday, May 27th, 4:20–6:00 PM, at Huangchaoyang Building B403 meeting room. Best of luck, Yuki!

Mar 2026

Congrats to Xue-Mei and Bai-Tao for their work published on bioRxiv, this is a collaborating project with Prof. Zhiyou Zong!

Mar 2026

Welcome to our new lab website!